Darién Province Vacations & Trips from $650

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Your Darién Province Vacation

Answer the call of adventure with a tailor-made vacation package to Darién Province. Wherever you're headed and whatever your plans are, get ready to experience a destination that'll make you truly feel alive. Start your trip to Darién Province by spending a few days exploring Santa Fe, one of the leading cities here. Start packing your suitcase, because your Darién Province vacation is only a few clicks away with Expedia.

The Latest Darién Province Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Nowhere

Nowhere

3 out of 5
Save 100% on your flight
Price was $959, price is now $650 per person
$650
per person
Nov 5 - Nov 12
found 1 day ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
9/10 Wonderful! (16 reviews)
What a uniqe location! Get up early, take your time to take in amazing birds and wildlife surrounding you!

Reviewed on Feb 28, 2025

Central Hotel Bocas del Toro

Central Hotel Bocas del Toro

3 out of 5
Price was $3,552, price is now $1,776 per person
$1,776
per person
Nov 5 - Nov 12
found 1 day ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
No reviews
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
Price was $2,544, price is now $1,400 per person
$1,400
per person
Nov 10 - Nov 17
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
9/10 Wonderful! (976 reviews)
An exquisite home base for an exploration of Casco Viejo. VERY reasonably priced for what you get.

Reviewed on Aug 30, 2025

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Bella Vista
Price was $1,262, price is now $856 per person
$856
per person
Nov 10 - Nov 17
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
9/10 Wonderful! (4,208 reviews)
The property was very clean and staff

Reviewed on Sep 1, 2025

La Coralina Island House

La Coralina Island House

3.5 out of 5
Save 100% on your flight
Price was $1,971, price is now $1,350 per person
$1,350
per person
Oct 18 - Oct 25
found 10 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9.4/10 Exceptional! (84 reviews)
Beautiful grounds and love the included yoga, meditation, and work outs. They provided free cooked to order breakfast with coffee and juice. Staff was friendly and helpful

Reviewed on Aug 30, 2025

Best Places to Vacation in Darién Province

1. Plan your dream getaway to Santa Fe

Santa Fe, located in the beautiful Darién Province of Panama, offers a unique and affordable vacation experience. Immerse yourself in the local atmosphere, where friendly locals welcome you with open arms. Explore the stunning natural landscapes, from lush rainforests to pristine rivers and waterfalls. Indulge in authentic Panamanian cuisine at the local eateries, offering delicious dishes at budget-friendly prices. Discover the rich culture and history of the area through visits to the nearby indigenous communities and museums. Santa Fe provides a tranquil and inexpensive getaway for those seeking a true Panamanian experience.

Darién Province Hotel Deals

Hospedaje casa cultural wounaan

Hospedaje casa cultural wounaan

2 out of 5
Panama canal, Puerto lara Darien, Santa Fe, Darien
Fully refundable
$17 nightly
The price is $19 total per night from Sep 7 to Sep 8
$19 total
Sep 7 - Sep 8
Total with taxes and fees
Hospedaje casa cultural wounaan
San Blas Big Orange Island "Narasgandub Dummad"

San Blas Big Orange Island "Narasgandub Dummad"

Guna Yala
Get rates
San Blas Big Orange Island "Narasgandub Dummad"
Tripsyala

Tripsyala

2.5 out of 5
Guna Yala, Ailigandí, Guna Yala
Get rates
Tripsyala
See all 9 properties in Darién Province
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Frequently asked questions

How much does a Darién Province vacation package cost?
From as little as $650, you can tailor make your Darién Province package the way you want. Simply combine hotels, flights and car rentals and we'll reward you with discounts.
How do I get a cheap travel package to Darién Province?
Secure flights that fit your busy schedule, add a hotel room to your booking and watch the savings stack up with a Darién Province vacation package. It's as simple as that! From hotels and flights to tours and rental cars, Expedia makes traveling on the cheap easy. And with over 550 air carriers and 1,000,000 hotel options around the world to pick from, you won't be short of choice.
How far in advance should I book my Darién Province vacation?
It's tricky picking the ideal time for airfares, but we normally say the earlier, the better. Many international flights on Expedia become available up to a year in advance. If you can't book ahead, don't worry. Cheap prices occasionally appear within a few weeks of departure dates.
What does an Expedia Darién Province travel package include?
Hotels, flights and a shiny set of wheels for all your road trip adventures. Simply pick and choose your favorite bundle and get access to incredible deals. Once you've made your booking, add on a couple of sightseeing tours and watch your savings grow. When it comes to planning your Darién Province break, the choice is all yours!
What should I know before booking a Darién Province travel package?
You'll score amazing savings when you combine your hotels, flights and rental cars into a travel package. Plus, booking everything in one spot makes trip planning easier. So why waste your time or money? Whether you're putting together a luxury city stay with your love or a budget solo adventure, have a look at our package deals today.
Can I choose my airline with a Darién Province Expedia vacation package?
Yes — that's the beauty of an Expedia package. You're the boss! We have access to more than 550 partner airlines all over the world, so you have lots of choice when arranging your Darién Province escape.
Does Expedia offer Book Now, Pay Later Darién Province vacation packages?
If you want to split the price of your flight and hotel over several installments, Expedia can help you out. Paying the total cost of your travel upfront isn't always the best way to budget for your getaway, so we've partnered with online lender Affirm to give you financial freedom. Book Now, Pay Later and take the worry out of saving to travel.
If I'm not able to travel, can I cancel my Darién Province vacation package?
If your vacation plans in Darién Province have been upended, it's good to know that it is possible to cancel or amend your booking. If you booked within the last 24 hours, you may be eligible for a refund. If your booking is older than that, your hotel, airline or car rental company may charge fees. For more information, visit our Customer Service Portal.

Discover the most popular places to visit in Darién Province

Pirre Station

You can find out about the history of La Palma when you stop by Pirre Station.

Pirre Station

What to do in Darién Province

Embera Village Day Tour, Chagres River & Waterfalls + Lunch, Fruits & Water

Embera Village Day Tour, Chagres River & Waterfalls + Lunch, Fruits & Water

$70
per adult
100% of travellers recommend
Embera Village Day Tour, Chagres River & Waterfalls + Lunch, Fruits & Water
See all activities in Darién Province
Explore a world of travel with Expedia

Explore a world of travel with Expedia

Other vacations you might like

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.